Aimovig (erenumab-aooe)

Product Name:

Aimovig (erenumab-aooe)

Categories: Neurology

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Table of Contents

Aimovig (erenumab)

Product Category

Neurology

Brand Name

Aimovig

Generic Name or Biosimilar

No

Active Ingredient

Erenumab

Prescription Status

Prescription-only in the United States, Mexico, and Canada.

Targeted Conditions

  • Migraine prevention in adults experiencing frequent or chronic migraines.
  • Reduces the number of migraine days per month and helps improve quality of life.

Off-Label Usage

  • Occasionally studied in cluster headaches and other headache disorders, though not approved for these uses.
  • May be considered in patients with refractory headaches when standard therapies fail.

Drug Classification Overview

Aimovig is a monoclonal antibody that targets and blocks the calcitonin gene-related peptide (CGRP) receptor. CGRP plays a key role in the onset and persistence of migraines. By blocking this receptor, Aimovig helps prevent migraines before they start.

Manufacturer in the USA, Mexico, and Canada

  • United States: Amgen Inc.
  • Canada: Novartis Pharma Canada Inc. (in partnership with Amgen)
  • Mexico: Novartis México S.A. de C.V.

Available Strengths and Dosage Forms – United States, Mexico, and Canada

Country Comparison – United States vs Mexico and Canada

  • Aimovig is approved in all three countries for the prevention of migraines.
  • Product branding and packaging may differ slightly between countries, but therapeutic use remains consistent.

Average Retail Price (Monthly Treatment) USA vs Mexico vs Canada

  • Canada: Typically 20–30% savings compared to U.S. pricing.
  • Mexico: Typically 25–35% savings compared to U.S. pricing.

Savings are approximate, based on 2025 price data. They may vary depending on availability, prescription requirements, supply chain, and whether cold-chain handling is required.

Where to Buy USA

  • Costco
  • CVS
  • Rite Aid
  • Walgreens
  • Walmart
  • Kroger
  • Albertsons
  • Sam’s Club
  • Publix
  • Target (via CVS Pharmacy)
  • Online mail-order specialty care pharmacies

Availability may vary depending on insurance coverage, specialty pharmacy networks, and prior authorization requirements.

Storage Requirements

  • Store in a refrigerator (2°C–8°C / 36°F–46°F).
  • Protect from light.
  • Do not freeze.
  • Allow to reach room temperature before injection.
  • Keep in the original carton until ready to use.

Shipping from Canada

This medication is accessed through fully licensed Canadian pharmacies regulated by Health Canada. All pharmacies included in the MedicalMex network undergo a rigorous review and verification process to ensure compliance with national standards, patient safety, and medication authenticity.

MedicalMex facilitates:

  • Prescription verification and fulfillment coordination
  • Secure, compliant medication logistics
  • Access to licensed Canadian pharmacists
  • Access to our network of certified physicians if a Telehealth consultation is needed
  • Case management, payment handling, and personalized boutique-level support
  • Cold chain shipping with next-generation temperature-monitored coolers, when required
  • Refill tracking and patient adherence programs

You are working directly with MedicalMex Inc., a U.S.-based company that helps eligible patients safely access affordable medications from Canada — with compliance and full-service concierge support at every step.

Buying from Mexico

This medication is also available through certified pharmacies in Mexico regulated by COFEPRIS (Mexico’s national health authority). All partners in the MedicalMex network must pass a rigorous review and certification process before being approved for patient access.

MedicalMex facilitates:

  • Transportation support to our affiliate clinic in Tijuana, Mexico
  • Prescription handling through licensed physicians within our certified network
  • Access to our network of accredited physicians if a Telehealth consultation is needed
  • Travel coordination, including flights and/or hotel reservations when required
  • Travel insurance
  • Cold chain shipping with advanced temperature-monitored coolers, when applicable
  • Personalized, boutique-level service
  • Refill tracking and patient adherence support

You are working directly with MedicalMex Inc., a U.S.-based company that manages every detail — from medical and travel logistics to prescription compliance — providing secure, affordable access to life-saving medications from Mexico.

Key Benefits

  • Reduces the number of monthly migraine days.
  • Easy-to-use, once-monthly injection.
  • Alternative for patients who do not respond to traditional migraine preventives.
  • Improves overall patient quality of life by reducing migraine burden.

Side Effects

Common side effects:

  • Injection site reactions (pain, redness, swelling)
  • Constipation
  • Muscle cramps or spasms

Serious but less common side effects:

  • Severe constipation requiring hospitalization
  • Allergic reactions, including rash or difficulty breathing
  • High blood pressure in some patients

Warnings and Precautions

  • Monitor for constipation, which can become severe.
  • Patients with a history of cardiovascular conditions should be closely monitored, as rare cases of hypertension have been reported.
  • Not recommended in patients with known hypersensitivity to erenumab.
  • Safety in pregnancy and breastfeeding has not been established.

Alternative Medications (by Indication)

  • Emgality (galcanezumab): CGRP inhibitor for migraine prevention.
  • Ajovy (fremanezumab): CGRP inhibitor for migraine prevention.
  • Topiramate: Oral medication often used off-label for migraine prevention.
  • Botox (onabotulinumtoxinA): Approved for chronic migraine prevention.

Medication FAQs

Aimovig is prescribed to prevent migraines in adults who experience frequent or chronic migraines.

It is given as a once-monthly subcutaneous (under the skin) injection using a prefilled autoinjector or syringe.

Some patients report fewer migraines within the first month, but it may take up to 3 months for full benefit.

Yes. It is often used alongside acute migraine treatments such as triptans.

Clinical studies suggest Aimovig is safe for long-term use, but patients should remain under medical supervision.

Take the missed dose as soon as you remember, then continue with your regular schedule. Do not double up doses.

Currently, Aimovig is only approved for adults 18 years and older.

Weight gain is not a common side effect of Aimovig.

Yes, Aimovig must be refrigerated. It should be allowed to reach room temperature before injection.

Yes. Patient support programs may be available in the U.S., Canada, and Mexico. MedicalMex can help patients explore affordable access options.