Eliquis (apixaban)

Product Name:

Eliquis (apixaban)

Categories: Cardiology, Hematology

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Table of Contents

Eliquis (apixaban)

Product Category

Oral Anticoagulant – Cardiovascular / Stroke Prevention

Brand Name

Eliquis

Generic Name or Biosimilar

No

Active Ingredient

Apixaban

Prescription Status

Prescription-only

Targeted Conditions

  • Deep vein thrombosis (DVT)
  • Pulmonary embolism (PE)
  • Stroke and systemic embolism in patients with nonvalvular atrial fibrillation (NVAF)
  • DVT and PE recurrence after initial treatment

It is commonly prescribed to lower the risk of stroke in patients with atrial fibrillation not caused by a heart valve issue.

Off-Label Usage

  • Postoperative thromboprophylaxis in certain surgical patients beyond labeled use
  • Patients with cancer-associated thrombosis (when anticoagulation is indicated)
  • Certain pediatric indications (under specialist guidance)

Drug Classification Overview

Eliquis is a direct oral anticoagulant (DOAC) belonging to the class of Factor Xa inhibitors.
It works by selectively blocking Factor Xa in the coagulation cascade, reducing the risk of blood clots forming in veins and arteries.

Manufacturer in the USA, Mexico, and Canada

USA: Bristol-Myers Squibb and Pfizer
Canada: Bristol-Myers Squibb Canada / Pfizer Canada
Mexico: Bristol-Myers Squibb de México S. de R.L. de C.V.

Available Strengths and Dosage Forms – United States, Mexico, and Canada

Country Comparison – United States vs Mexico and Canada

  • Same active ingredient and clinical effectiveness across USA, Mexico, and Canada
  • Packaging, language, and dosage labeling may vary
  • Canadian and Mexican versions may have blister or bottle differences
  • All versions manufactured under GMP standards

Average Retail Price (Monthly Treatment)

Mexico: ~50%–65% savings vs U.S. retail
Canada: ~40%–55% savings vs U.S. retail

Savings may vary depending on availability, strength, manufacturer, cold chain status, or controlled drug regulations.

Where to Buy USA

  • CVS, Walgreens, Rite Aid, Walmart, Costco, Kroger, Albertsons, Sam’s Club, Publix, Target (via CVS Pharmacy), and online specialty pharmacies

Availability may vary depending on insurance coverage and regional pharmacy networks.

Storage Requirements

  • Store at room temperature (15°C to 30°C / 59°F to 86°F)
  • Keep in original packaging until use
  • Protect from moisture and direct sunlight

Key Benefits

  • Proven to reduce the risk of stroke in NVAF
  • Lower risk of major bleeding vs warfarin
  • Fixed dosing without routine monitoring
  • Convenient oral tablet format
  • Rapid onset and predictable anticoagulant effect

Shipping from Canada

This medication is accessed through fully licensed Canadian pharmacies regulated by Health Canada. All pharmacies included in the MedicalMex network undergo a rigorous review and verification process to ensure compliance with national standards, patient safety, and medication authenticity.

MedicalMex facilitates:

  • Prescription verification and fulfillment coordination
  • Secure, compliant medication logistics
  • Access to licensed Canadian pharmacists
  • Access to certified physicians for Telehealth if needed
  • Case management and boutique-level support
  • Cold chain shipping when required
  • Refill tracking and adherence programs

Buying from Mexico

This medication is also available through certified pharmacies in Mexico regulated by COFEPRIS. All partners in the MedicalMex network must pass a rigorous certification process before being approved for patient access.

MedicalMex facilitates:

  • Transportation support to our affiliate clinic in Tijuana, Mexico
  • Prescription handling with licensed physicians
  • Telehealth consultations if needed
  • Travel coordination when required
  • Travel insurance
  • Cold chain shipping when applicable
  • Refill tracking and adherence support

Side Effects

  • Common: Minor bleeding (nosebleeds, bruising, gum bleeding); Nausea
  • Moderate: Anemia; Hematuria; Menstrual abnormalities
  • Serious: Major bleeding (GI, intracranial); Hypersensitivity (rare); Thrombocytopenia

Seek immediate care if you experience uncontrolled bleeding, dizziness, or signs of internal bleeding.

Warnings and Precautions

  • Contraindicated in patients with active bleeding
  • Caution in renal or hepatic impairment
  • Avoid abrupt discontinuation
  • Not recommended with certain CYP3A4 or P-gp inhibitors/inducers
  • Pregnancy/breastfeeding only if clearly needed
  • Routine INR not required, but monitor renal function

Alternative Medications (by Indication)

Xarelto (rivaroxaban)
Pradaxa (dabigatran)
Savaysa (edoxaban)
Warfarin (Coumadin)
Lovenox (enoxaparin)
Arixtra (fondaparinux)

Medication FAQs

Eliquis has been shown to have a lower risk of major bleeding compared to warfarin, especially in patients with atrial fibrillation.

Some patients take it short-term (e.g., 3–6 months for DVT/PE), while others may need lifelong therapy.

Alcohol can increase bleeding risk. Limit or avoid alcohol and consult your doctor.

No routine INR tests needed. Kidney function and bleeding risk should be checked periodically.

Take as soon as you remember, unless close to next dose. Do not double up.

Yes, it has the same active ingredient, produced by the same manufacturers. Packaging may differ.

Yes, if sourced through MedicalMex verified pharmacies (COFEPRIS or Health Canada regulated).

No. A valid prescription is required, though MedicalMex can connect you with certified physicians if needed.

Yes, it’s a Factor Xa inhibitor, a newer-generation blood thinner.

Concierge services including physician access, logistics, prescription validation, transportation, cold chain shipping, and refill management.